C-ANCA-positive IgG fraction from patients with Wegener's granulomatosis induces lung vasculitis in rats

The aim of the present study was to analyse in rats the ability of C-ANCA-positive IgG fraction in triggering inflammatory response on pulmonary tissue. Wistar rats (n = 18) were injected via the the internal jugular vein with 20 mg of total C-ANCA-positive IgG fraction isolated from serum of three...

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Detalhes bibliográficos
Main Authors: WEIDEBACH, W, VIANA, V S T, LEON, E P, BUENO, C, LEME, A S, ARANTES-COSTA, F M, MARTINS, M A, SALDIVA, P H N, BONFA, E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
Assuntos:
Animal Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906412/
https://ncbi.nlm.nih.gov/pubmed/12100022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2002.01888.x
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