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Predominance of IgG1 and IgG4 subclasses of anti-neutrophil cytoplasmic autoantibodies (ANCA) in patients with Wegener's granulomatosis and clinically related disorders.

In view of the supposed hypersensitivity, the elevated levels of IgE, and the occurrence of eosinophilia reported in Wegener's granulomatosis and related conditions, we studied the IgG subclass distribution of ANCA directed against a 29-kD serine protease and myeloperoxidase (MPO) in 41 untreat...

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Detalhes bibliográficos
Main Authors: Brouwer, E, Tervaert, J W, Horst, G, Huitema, M G, van der Giessen, M, Limburg, P C, Kallenberg, C G
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1535341/
https://ncbi.nlm.nih.gov/pubmed/1848489
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