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Anti-CD45 isoform antibodies enhance phagocytosis and gene expression of IL-8 and TNF-α in human neutrophils by differential suppression on protein tyrosine phosphorylation and p56(lck) tyrosine kinase
To determine the biological functions of membrane expressed CD45 isoforms on polymorphonuclear neutrophils (PMN), the monoclonal IgG F(ab′)(2) antibody against CD45, CD45RA or CD45RO was used as surrogate ligand for binding with these molecules on PMN. We found 99·5 ± 3·2%, 42·3 ± 5·8% and 96·7 ± 2·...
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Asıl Yazarlar: | , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
Blackwell Science Inc
2002
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1906411/ https://ncbi.nlm.nih.gov/pubmed/12100025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2002.01907.x |
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