Elevated monocytic IL-12 and TNF-α production in Wegener’s granulomatosis is normalized by cyclophosphamide and corticosteroid therapy

Wegener’s granulomatosis (WG) is characterized by a predominance of the type 1 T-helper cell (Th1) response. We have studied monocytic cytokine expression in untreated patients and in patients who did not respond to prior methotrexate or trimethoprim-sulphamethoxazole therapy, i.e. patients with act...

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Autori principali: LAMPRECHT, P, KUMANOVICS, G, MUELLER, A, CSERNOK, E, KOMOCSI, A, TRABANDT, A, GROSS, W L, SCHNABEL, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2002
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906358/
https://ncbi.nlm.nih.gov/pubmed/11982607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2002.01801.x
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