Lidocaine inhibits secretion of IL-8 and IL-1β and stimulates secretion of IL-1 receptor antagonist by epithelial cells

Lidocaine and related local anaesthetics have been shown to be effective in the treatment of ulcerative colitis (UC). However, the mechanisms underlying their therapeutic effect are poorly defined. Intestinal epithelial cells play an important role in the mucosal inflammatory response that leads to...

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Bibliografiske detaljer
Main Authors: LAHAV, M, LEVITE, M, BASSANI, L, LANG, A, FIDDER, H, TAL, R, BAR-MEIR, S, MAYER, L, CHOWERS, Y
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2002
Fag:
Basic Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906346/
https://ncbi.nlm.nih.gov/pubmed/11876744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2002.01747.x
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