Lidocaine inhibits secretion of IL-8 and IL-1β and stimulates secretion of IL-1 receptor antagonist by epithelial cells

Lidocaine and related local anaesthetics have been shown to be effective in the treatment of ulcerative colitis (UC). However, the mechanisms underlying their therapeutic effect are poorly defined. Intestinal epithelial cells play an important role in the mucosal inflammatory response that leads to...

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Detalhes bibliográficos
Main Authors: LAHAV, M, LEVITE, M, BASSANI, L, LANG, A, FIDDER, H, TAL, R, BAR-MEIR, S, MAYER, L, CHOWERS, Y
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
Assuntos:
Basic Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906346/
https://ncbi.nlm.nih.gov/pubmed/11876744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2002.01747.x
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