Intranasal BCG vaccination protects BALB/c mice against virulent Mycobacterium bovis and accelerates production of IFN-γ in their lungs

Local immune reactivity in the lungs of BALB/c mice was studied following (i) intranasal (i.n.) vaccination with Mycobacterium bovis BCG, (ii) intravenous (i.v.) challenge with a virulent M. bovis field isolate and (iii) i.n. vaccination with M. bovis BCG followed by i.v. challenge with an M. bovis...

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Autores principales: Lyadova, I V, Vordermeier, H M, Eruslanov, E B, Khaidukov, S V, Apt, A S, Hewinson, R G
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2001
Materias:
Immunity to Infection
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906185/
https://ncbi.nlm.nih.gov/pubmed/11703371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2001.01667.x
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