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C1q-bearing immune complexes induce IL-8 secretion in human umbilical vein endothelial cells (HUVEC) through protein tyrosine kinase- and mitogen-activated protein kinase-dependent mechanisms: evidence that the 126 kD phagocytic C1q receptor mediates immune complex activation of HUVEC

Endothelial cells play a pivotal role in the initiation and perpetuation of inflammation. C1q, the first component of the classical pathway of complement, is a potent stimulus leading to endothelial cell activation and cytokine production. The specific cellular mechanisms through which endothelial c...

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Detalhes bibliográficos
Main Authors: Xiao, S, Xu, C, Jarvis, J N
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906143/
https://ncbi.nlm.nih.gov/pubmed/11531942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2001.01597.x
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