Selection of single chain variable fragments (scFv) against the glycoprotein antigen of the rabies virus from a human synthetic scFv phage display library and their fusion with the Fc region of human IgG1

We have prepared human recombinant antibody molecules against the glycoprotein antigen of the rabies virus (GPRV) based on the single chain variable fragment (scFv) format. Anti-GPRV scFvs were selected from a human synthetic scFv phage display library with a repertoire of approximately 10(9) specif...

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Bibliographische Detailangaben
Hauptverfasser: Ray, K, Embleton, M J, Jailkhani, B L, Bhan, M K, Kumar, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2001
Schlagworte:
Immunity to Infection
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906113/
https://ncbi.nlm.nih.gov/pubmed/11472431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2001.01515.x
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