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Selection of single chain variable fragments (scFv) against the glycoprotein antigen of the rabies virus from a human synthetic scFv phage display library and their fusion with the Fc region of human IgG1

We have prepared human recombinant antibody molecules against the glycoprotein antigen of the rabies virus (GPRV) based on the single chain variable fragment (scFv) format. Anti-GPRV scFvs were selected from a human synthetic scFv phage display library with a repertoire of approximately 10(9) specif...

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Autori principali: Ray, K, Embleton, M J, Jailkhani, B L, Bhan, M K, Kumar, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906113/
https://ncbi.nlm.nih.gov/pubmed/11472431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2001.01515.x
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