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Epstein-Barr virus EBNA3A and EBNA3C proteins both repress RBP-J kappa-EBNA2-activated transcription by inhibiting the binding of RBP-J kappa to DNA.

Following infection by Epstein-Barr virus (EBV), the production of viral nuclear proteins EBNA1, EBNA2, EBNA3A, and EBNA3C and the viral membrane protein LMP1 is essential for the permanent proliferation of primary B lymphocytes to occur. Among these, the transcription factor EBNA2 is central to the...

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Autors principals: Waltzer, L, Perricaudet, M, Sergeant, A, Manet, E
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC190609/
https://ncbi.nlm.nih.gov/pubmed/8709211
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