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Epstein-Barr virus EBNA3A and EBNA3C proteins both repress RBP-J kappa-EBNA2-activated transcription by inhibiting the binding of RBP-J kappa to DNA.

Following infection by Epstein-Barr virus (EBV), the production of viral nuclear proteins EBNA1, EBNA2, EBNA3A, and EBNA3C and the viral membrane protein LMP1 is essential for the permanent proliferation of primary B lymphocytes to occur. Among these, the transcription factor EBNA2 is central to the...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Waltzer, L, Perricaudet, M, Sergeant, A, Manet, E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190609/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8709211/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.9.5909-5915.1996
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