The Residues between the Two Transformation Effector Sites of Epstein-Barr Virus Latent Membrane Protein 1 Are Not Critical for B-Lymphocyte Growth Transformation

Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1) is essential for EBV-mediated transformation of primary B lymphocytes. LMP1 spontaneously aggregates in the plasma membrane and enables two transformation effector sites (TES1 and TES2) within the 200-amino-acid cytoplasmic carboxyl terminus...

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Bibliographic Details
Main Authors: Izumi, Kenneth M., McFarland, Ellen Cahir, Riley, Elisabeth A., Rizzo, Danielle, Chen, Yuzhi, Kieff, Elliott
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Transformation and Oncogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC113040/
https://ncbi.nlm.nih.gov/pubmed/10559303
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