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Two chaperone sites in Hsp90 differing in substrate specificity and ATP dependence

The abundant molecular chaperone Hsp90 is a key regulator of protein structure in the cytosol of eukaryotic cells. Although under physiological conditions a specific subset of proteins is substrate for Hsp90, under stress conditions Hsp90 seems to perform more general functions. However, the underly...

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Bibliografiske detaljer
Main Authors: Scheibel, Thomas, Weikl, Tina, Buchner, Johannes
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC19060/
https://ncbi.nlm.nih.gov/pubmed/9465043
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