Opsonizing antibodies (IgG1) up-regulate monocyte proinflammatory cytokines tumour necrosis factor-alpha (TNF-α) and IL-6 but not anti-inflammatory cytokine IL-10 in mycobacterial antigen-stimulated monocytes—implications for pathogenesis

Cachexia is one of the prominent features of advanced tuberculosis (TB) seen in association with increased expression of the monokine TNF-α. Several mycobacterial proteins, including PPD, stimulate TNF-α secretion from monocytes. Host factors that may play a role in cytokine expression from monocyte...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Hussain, R, Shiratsuchi, H, Phillips, M, Ellner, J, Wallis, R S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2001
Soggetti:
Immunity to Infection
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905980/
https://ncbi.nlm.nih.gov/pubmed/11207650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2001.01439.x
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi