Induction of lymphocyte apoptosis in rat liver allograft with ongoing rejection by FTY720

The action mechanism of FTY720, a novel immunosuppressant, is completely different from conventional immunosuppressants. The drug, which triggers apoptosis in murine and human lymphocytes, has a potent immunosuppressive activity to prevent allograft rejection without any severe side-effect. The pres...

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Main Authors: Li, X -K, Tamura, A, Fujino, M, Guo, L, Kakefuda, T, Funeshima, N, Enosawa, S, Amari, M, Naoe, S, Amemiya, H, Suzuki, S
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2001
Teme:
Transplantation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905974/
https://ncbi.nlm.nih.gov/pubmed/11207666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2001.01434.x
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