The human immunodeficiency virus type 1 capsid p2 domain confers sensitivity to the cyclophilin-binding drug SDZ NIM 811.

Human immunodeficiency virus type 1 (HIV-1) specifically incorporates the host cell peptidyl-prolyl isomerase cyclophilin A into virions via contacts with the capsid (CA) domain of the Gag polyprotein Pr55gag. The immunosuppressant drug cyclosporin A and the nonimmunosuppressive cyclosporin A analog...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Dorfman, T, Göttlinger, H G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190588/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8709190/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.9.5751-5757.1996
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