A novel point mutation in CD18 causing the expression of dysfunctional CD11/CD18 leucocyte integrins in a patient with leucocyte adhesion deficiency (LAD)

Leucocyte adhesion deficiency type 1 (LAD-1) is characterized by the incapacity of leucocytes to carry out their adhesion functions via their CD11/CD18 antigens, which are also referred to as the leucocyte integrins. The patients generally suffer from poor wound healing and recurrent bacterial and f...

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Autori principali: Mathew, E C, Shaw, J M, Bonilla, F A, Law, S K A, Wright, D A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2000
Soggetti:
Immunodeficiency
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905666/
https://ncbi.nlm.nih.gov/pubmed/10886250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01277.x
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