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Hydroxyurea inhibits the transactivation of the HIV-long-terminal repeat (LTR) promoter

HIV-1 gene expression is regulated by the promoter/enhancer located within the U3 region of the proviral 5′ LTR that contains multiple potential cis-acting regulatory sites. Here we describe that the inhibitor of the cellular ribonucleoside reductase, hydroxyurea (HU), inhibited phorbol myristate ac...

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Autori principali: Calzado, M A, Macho, A, Lucena, C, Muñoz, E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905657/
https://ncbi.nlm.nih.gov/pubmed/10792382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01203.x
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