Intra-articular IL-10 gene transfer regulates the expression of collagen-induced arthritis (CIA) in the knee and ipsilateral paw

We studied the effects of local IL-10 application, introduced by a recombinant human type 5 adenovirus vector, in the mouse knee joint during the early phase of CIA. One intra-articular injection with the IL-10-expressing virus (Ad5E1mIL-10) caused substantial over-expression of IL-10 in the mouse k...

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Detalhes bibliográficos
Main Authors: Lubberts, E, Joosten, L A B, Van Den Bersselaar, L, Helsen, M M A, Bakker, A C, Xing, Z, Richards, C D, Van Den Berg, W B
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Neuroimmunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905648/
https://ncbi.nlm.nih.gov/pubmed/10792391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01217.x
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