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Nuclear factor-κ B activity and intestinal inflammation in dextran sulphate sodium (DSS)-induced colitis in mice is suppressed by gliotoxin

In acute DSS-induced colitis nuclear factor (NF)-κ B-dependent inflammatory cytokines including IL-1 and tumour necrosis factor-alpha (TNF-α) are up-regulated. Here we examined the effects of gliotoxin, a fungal metabolite known to inhibit NF-κ B activity, on cytokine production by a mouse cell syst...

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Detalhes bibliográficos
Main Authors: Herfarth, H, Brand, K, Rath, H C, Rogler, G, Schölmerich, J, Falk, W
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905603/
https://ncbi.nlm.nih.gov/pubmed/10759764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01184.x
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