Therapeutic effect of intracolonically administered nuclear factor κ B (p65) antisense oligonucleotide on mouse dextran sulphate sodium (DSS)-induced colitis

Cytokines such as IL-1, tumour necrosis factor-alpha (TNF-α), IL-6 and IL-8 are increased in inflamed colonic mucosa after administration of mouse DSS. Nuclear factor κ B (NF-κ B) is a transcription factor which regulates the expression of these cytokine genes. The effect of intracolonically adminis...

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Detalhes bibliográficos
Main Authors: Murano, M, Maemura, K, Hirata, I, Toshina, K, Nishikawa, T, Hamamoto, N, Sasaki, S, Saitoh, O, Katsu, K
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Gut Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905625/
https://ncbi.nlm.nih.gov/pubmed/10759763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01183.x
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