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Expression of costimulatory molecules CD80 and CD86 and their receptors CD28, CTLA-4 on malignant ascites CD3(+) tumour-infiltrating lymphocytes (TIL) from patients with ovarian and other types of peritoneal carcinomatosis

Costimulation of T lymphocytes by the leucocyte surface molecules CD80 and CD86 expressed on antigen-presenting cells (APC) is required for the development of T cell responses. The CD28 and CTLA-4 molecules on T cells serve as receptors for the CD80 and CD86 costimulatory antigens. We have examined...

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Autors principals: Melichar, B, Nash, M A, Lenzi, R, Platsoucas, C D, Freedman, R S
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905534/
https://ncbi.nlm.nih.gov/pubmed/10606960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01105.x
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