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In vitro activated CD4(+) T cells from interferon-gamma (IFN-γ)-deficient mice induce intestinal inflammation in immunodeficient hosts
To investigate the role of IFN-γ in the immunopathogenesis of inflammatory bowel disease (IBD), severe combined immunodeficient (SCID) mice were transplanted with in vitro activated CD4(+) T cells from either wild-type (WT) or IFN-γ-deficient (IFN-γKO) BALB/c mice. In vitro, the two types of T cells...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
1999
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1905411/ https://ncbi.nlm.nih.gov/pubmed/10540183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.01058.x |
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