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In vitro activated CD4(+) T cells from interferon-gamma (IFN-γ)-deficient mice induce intestinal inflammation in immunodeficient hosts

To investigate the role of IFN-γ in the immunopathogenesis of inflammatory bowel disease (IBD), severe combined immunodeficient (SCID) mice were transplanted with in vitro activated CD4(+) T cells from either wild-type (WT) or IFN-γ-deficient (IFN-γKO) BALB/c mice. In vitro, the two types of T cells...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bregenholt, S, Brimnes, J, Nissen, M H, Claesson, M H
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905411/
https://ncbi.nlm.nih.gov/pubmed/10540183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.01058.x
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