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Sustained inflammation and differential expression of interferons type I and III in PVM-infected interferon-gamma (IFNγ) gene-deleted mice

Interferon gamma (IFNγ) has complex immunomodulatory and antiviral properties. While IFNγ is detected in the airways in response to infection with the pneumovirus pathogen, pneumonia virus of mice (PVM; Family Paramyxoviridae), its role in promoting disease has not been fully explored. Here, we eval...

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Dettagli Bibliografici
Pubblicato in:Virology
Autori principali: Glineur, Stephanie F., Bowen, Aaron B., Percopo, Caroline M., Garcia-Crespo, Katia E., Dyer, Kimberly D., Ochkur, Sergei I., Lee, Nancy A., Lee, James J., Domachowske, Joseph B., Rosenberg, Helene F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253980/
https://ncbi.nlm.nih.gov/pubmed/25173090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.07.039
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