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Depletion of liver and splenic macrophages reduces the lethality of Shiga toxin-2 in a mouse model

The haemolytic uraemic syndrome (HUS) is a clinical syndrome consisting of haemolytic anaemia, thrombocytopenia, and acute renal insufficiency. HUS is the most frequent cause of acute renal failure in childhood. It has been previously suggested that the presence of Shiga toxin (Stx) is necessary but...

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Detalhes bibliográficos
Main Authors: Palermo, M S, Alves Rosa, M S, Van Rooijen, N, Isturiz, M A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905309/
https://ncbi.nlm.nih.gov/pubmed/10361235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00925.x
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