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Alzheimer's β-amyloid peptides can activate the early components of complement classical pathway in a C1q-independent manner

β-Amyloid (β-A) accumulates in the brain of patients with Alzheimer's disease (AD) and is presumably involved in the pathogenesis of this disease, on account of its neurotoxicity and complement-activating ability. Although assembly of β-A in particular aggregates seems to be crucial, soluble no...

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מידע ביבליוגרפי
Main Authors: Bergamaschini, L, Canziani, S, Bottasso, B, Cugno, M, Braidotti, P, Agostoni, A
פורמט: Artigo
שפה:Inglês
יצא לאור: Blackwell Science Inc 1999
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905247/
https://ncbi.nlm.nih.gov/pubmed/10193429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00835.x
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