Anti-proteinase-3 (PR3) antibodies (C-ANCA) recognize various targets on the human umbilical vein endothelial cell (HUVEC) membrane

Numerous studies suggest that C-ANCA are directly pathogenic in vasculitis by activating leucocytes (oxidative burst, enzyme release, endothelial cytotoxicity, etc.). We and others have shown that C-ANCA can also directly activate HUVEC, but the precise target on HUVEC is unknown. We show in this st...

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Autors principals: De Bandt, M, Meyer, O, Dacosta, L, Elbim, C, Pasquier, C
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 1999
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905152/
https://ncbi.nlm.nih.gov/pubmed/9933466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1999.00799.x
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