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IL-6 receptor blockage inhibits the onset of autoimmune kidney disease in NZB/W F(1) mice

In the present study, we examined the preventive effect of anti-mouse IL-6 receptor (IL-6R) antibody, MR16-1, on the development of autoimmune kidney disease in female NZB/W F(1) (BWF(1)) mice. Immunological tolerance to MR16-1 or isotype-matched control antibody, KH-5, was induced by the simultaneo...

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Detalhes bibliográficos
Main Authors: Mihara, M, Takagi, N, Takeda, Y, Ohsugi, Y
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904997/
https://ncbi.nlm.nih.gov/pubmed/9649207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00612.x
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