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Epitopes expressed in myasthenia gravis (MG) thymomas are not recognized by patients' T cells or autoantibodies

Most thymic epithelial tumours that associate with MG express an epitope that resembles the sequence α373–380 from the cytoplasmic loop of the acetylcholine receptor (AChR). It has been proposed that sensitization to this linear epitope initiates autoimmunity to the AChR in thymoma-associated MG. We...

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Bibliografiske detaljer
Main Authors: Nagvekar, N, Jacobson, L W, Willcox, N, Vincent, A
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904952/
https://ncbi.nlm.nih.gov/pubmed/9566784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00556.x
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