Cytomegalovirus (CMV) infection in AIDS patients is associated with a CD3 receptor-mediated T cell hyporesponsiveness

HIV(+) individuals with human CMV (HCMV) reactivation have a CD3 receptor-mediated T cell hyporesponsiveness when compared with CD4-matched HIV(+) and HCMV(−)control groups. The impairment of proliferation was not reversed by exogenous IL-2. A typical increase in NFκB expression was observed followi...

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Detalhes bibliográficos
Main Authors: Rowbottom, A W, Lepper, M W, Sharpstone, D, Gazzard, B
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1998
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904875/
https://ncbi.nlm.nih.gov/pubmed/9528899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00515.x
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