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The role of IL-13 in IgE synthesis by allergic asthma patients

IgE antibodies play a crucial role in allergic type I reactions. Only IL-4 and IL-13 are able to induce an immunoglobulin isotype switch to IgE in B cells. A major question is to what extent these cytokines contribute to the production of IgE in allergic patients. To address this question we used an...

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Detalhes bibliográficos
Main Authors: Van Der Pouw Kraan, T C T M, Van Der Zee, J S, Boeije, L C M, DE Groot, E R, Stapel, S O, Aarden, L A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904850/
https://ncbi.nlm.nih.gov/pubmed/9472672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00471.x
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