Cross-linking of antigen receptor via Ig-β (B29, CD79b) can induce both positive and negative signals in CD40-activated human B cells

Antigen-dependent activation of B lymphocytes is mediated through surface immunoglobulins and their associated molecules Ig-α (CD79a, Mb1) and Ig-β (CD79b, B29). Here we show that an antibody directed against the extracellular part of human Ig-β can, when cross-linked by CD32-transfected L cells, in...

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Detalhes bibliográficos
Main Authors: VAN KOOTEN, C, GALIBERT, L, SEON, B K, GARRONE, P, LIU, Y-J, BANCHEREAU, J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1997
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904830/
https://ncbi.nlm.nih.gov/pubmed/9409658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.4201436.x
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