Artificial antigen-presenting cells engineered by recombinant vaccinia viruses expressing antigen, MHC class II, and costimulatory molecules elicit proliferation of CD4(+) lymphocytes in vitro

The current study was designed to test the ability of recombinant Vaccinia virus (rVV) encoding essential components of an artificial antigen-presenting cell to activate antigen-specific T cells in vitro. We have constructed a set of rVV encoding separately or in combination a CD4(+) T cell-specific...

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Main Authors: OERTLI, D, MARTI, W R, NORTON, J A, TSUNG, K
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 1997
Assuntos:
Editorial Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904783/
https://ncbi.nlm.nih.gov/pubmed/9353162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.5061405.x
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