Membrane targeting of cGMP-dependent protein kinase is required for cystic fibrosis transmembrane conductance regulator Cl(−) channel activation

A recently cloned isoform of cGMP-dependent protein kinase (cGK), designated type II, was implicated as the mediator of cGMP-provoked intestinal Cl(−) secretion based on its localization in the apical membrane of enterocytes and on its capacity to activate cystic fibrosis transmembrane conductance r...

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Hlavní autoři: Vaandrager, Arie. B., Smolenski, Albert, Tilly, Ben C., Houtsmuller, Adriaan B., Ehlert, Ehrich M. E., Bot, Alice G. M., Edixhoven, Marcel, Boomaars, Wendy E. M., Lohmann, Suzanne M., de Jonge, Hugo R.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1998
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC19047/
https://ncbi.nlm.nih.gov/pubmed/9465038
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