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Heterozygous C8β complement deficiency does not predispose to meningococcal disease

We have identified 42 Russian patients with homozygous C8β complement component deficiency, all of whom had experienced at least one episode of systemic meningococcal disease. About 90% of these individuals have a C → T exchange in exon 9, leading to a premature stop codon. If, like the homozygous-d...

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Bibliografiska uppgifter
Huvudupphovsmän: PLATONOV, A E, SHIPULIN, G A, JU. SHIPULINA, O, VERSHININA, I V, DENSEN, P
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Science Inc 1997
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904676/
https://ncbi.nlm.nih.gov/pubmed/9182898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.3711263.x
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