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Heterozygous C8β complement deficiency does not predispose to meningococcal disease

We have identified 42 Russian patients with homozygous C8β complement component deficiency, all of whom had experienced at least one episode of systemic meningococcal disease. About 90% of these individuals have a C → T exchange in exon 9, leading to a premature stop codon. If, like the homozygous-d...

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Detalhes bibliográficos
Main Authors: PLATONOV, A E, SHIPULIN, G A, JU. SHIPULINA, O, VERSHININA, I V, DENSEN, P
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904676/
https://ncbi.nlm.nih.gov/pubmed/9182898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.3711263.x
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