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Expansion of restricted cellular immune responses to HIV-1 envelope by vaccination: IL-7 and IL-12 differentially augment cellular proliferative responses to HIV-1

The failure of immune effector mechanisms to control HIV-1 infection has important consequences for the human host. In a randomized cohort of HIV-infected patients, there was striking in vitro restriction of the proliferative response to HIV-1 envelope protein (Env), gp160; only 34% of patients reco...

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Detalhes bibliográficos
Main Authors: KIM, J H, LOVELAND, J E, SITZ, K V, RATTO KIM, S, MCLINDEN, R J, TENCER, K, DAVIS, K, BURKE, D S, BOSWELL, R N, REDFIELD, R R, BIRX, D L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904649/
https://ncbi.nlm.nih.gov/pubmed/9158092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.d01-1006.x
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