Neutralization of tumour necrosis factor (TNF) but not of IL-1 reduces inflammation in chronic dextran sulphate sodium-induced colitis in mice

The cytokines TNF and IL-1 have been implicated as mediators of the inflammatory processes in patients with inflammatory bowel disease (IBD). To investigate the role of these cytokines in mucosal inflammation we used anti-cytokine strategies in a mouse model of acute and chronic colitis. Mice which...

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Bibliographic Details
Main Authors: KOJOUHAROFF, G, HANS, W, OBERMEIER, F, MÄNNEL, D N, ANDUS, T, SCHÖLMERICH, J, GROSS, V, FALK, W
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 1997
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904573/
https://ncbi.nlm.nih.gov/pubmed/9030875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.1997.291-ce1184.x
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