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Human autoimmune anti-proteinase 3 scFv from a phage display library

This is the first study describing recombinant human antibody fragments directed to the autoantigen proteinase 3 (PR3) from an immune B cell source. Detection of these autoantibodies has proven valid for the diagnosis and monitoring of Wegener's granulomatosis. The described antibody fragment (...

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Autores principales: FINNERN, R, PEDROLLO, E, FISCH, I, WIESLANDER, J, MARKS, J D, LOCKWOOD, C M, OUWEHAND, W H
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904567/
https://ncbi.nlm.nih.gov/pubmed/9030863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.1997.254-ce1127.x
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