Transcriptional regulation of the distal promoter of the rat pyruvate carboxylase gene by hepatocyte nuclear factor 3β/Foxa2 and upstream stimulatory factors in insulinoma cells

PC (pyruvate carboxylase) plays a crucial role in intermediary metabolism including glucose-induced insulin secretion in pancreatic islets. In the present study, we identified two regions of the 1.2 kb distal promoter, the −803/−795 site and the −408/−403 E-box upstream of the transcription start si...

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Main Authors: Boonsaen, Thirajit, Rojvirat, Pinnara, Surinya, Kathy H., Wallace, John C., Jitrapakdee, Sarawut
Formáid: Artigo
Teanga:Inglês
Foilsithe: Portland Press Ltd. 2007
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904523/
https://ncbi.nlm.nih.gov/pubmed/17408383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070276
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