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Insight into gene fusion from molecular dynamics simulation of fused and un-fused IGPS (Imidazole Glycerol Phosphate Synthetase)

Gene fusion produces proteins with novel structural architectures during evolution. Recent comparative genome analysis shows several cases of fusion÷fission across distant phylogeny. However, the selection forces driving gene fusion are not fully understood due to the lack of structural, dynamics an...

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Bibliographic Details
Main Authors: Yiting, Yu, Lei, Li, Sakharkar, Meena Kishore, Kangueane, Pandjassarame
Format: Artigo
Language:Inglês
Published: Biomedical Informatics Publishing Group 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904513/
https://ncbi.nlm.nih.gov/pubmed/17611615
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