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Oxidative metabolism and PGC-1β attenuate macrophage-mediated inflammation

Complex interplay between T helper (Th) cells and macrophages contributes to the formation and progression of atherosclerotic plaques. While Th1 cytokines promote inflammatory activation of lesion macrophages, Th2 cytokines attenuate macrophage-mediated inflammation and enhance their repair function...

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Detalhes bibliográficos
Main Authors: Vats, Divya, Mukundan, Lata, Odegaard, Justin I., Zhang, Lina, Smith, Kristi L., Morel, Christine R., Greaves, David R., Murray, Peter J., Chawla, Ajay
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904486/
https://ncbi.nlm.nih.gov/pubmed/16814729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2006.05.011
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