AP1 enhances polyomavirus DNA replication by promoting T-antigen-mediated unwinding of DNA.
An early step in the initiation of polyomavirus DNA replication is viral large-T-antigen-mediated unwinding of the origin. We report that components of the AP1 transcription factor, Fos and Jun, interact with T antigen in vitro to enhance unwinding of the viral origin. This provides a biochemical ba...
Gespeichert in:
| Veröffentlicht in: | J Virol |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
1996
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190441/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8763994/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.8.4914-4918.1996 |
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