AP1 enhances polyomavirus DNA replication by promoting T-antigen-mediated unwinding of DNA.

An early step in the initiation of polyomavirus DNA replication is viral large-T-antigen-mediated unwinding of the origin. We report that components of the AP1 transcription factor, Fos and Jun, interact with T antigen in vitro to enhance unwinding of the viral origin. This provides a biochemical ba...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Guo, W, Tang, W J, Bu, X, Bermudez, V, Martin, M, Folk, W R
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1996
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190441/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8763994/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.8.4914-4918.1996
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