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Chain-reaction Ca(2+) signaling in the heart

Mutations in Ca(2+)-handling proteins in the heart have been linked to exercise-induced sudden cardiac death. The best characterized of these have been mutations in the cardiac Ca(2+) release channel known as the ryanodine receptor type 2 (RyR2). RyR2 mutations cause “leaky” channels, resulting in d...

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Detalles Bibliográficos
Main Authors: Györke, Sandor, Hagen, Brian M., Terentyev, Dmitry, Lederer, W. Jonathan
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904329/
https://ncbi.nlm.nih.gov/pubmed/17607353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32496
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