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Chain-reaction Ca(2+) signaling in the heart
Mutations in Ca(2+)-handling proteins in the heart have been linked to exercise-induced sudden cardiac death. The best characterized of these have been mutations in the cardiac Ca(2+) release channel known as the ryanodine receptor type 2 (RyR2). RyR2 mutations cause “leaky” channels, resulting in d...
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Hauptverfasser: | , , , |
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Format: | Artigo |
Sprache: | Inglês |
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American Society for Clinical Investigation
2007
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1904329/ https://ncbi.nlm.nih.gov/pubmed/17607353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32496 |
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