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Hin-mediated DNA knotting and recombining promote replicon dysfunction and mutation

BACKGROUND: The genetic code imposes a dilemma for cells. The DNA must be long enough to encode for the complexity of an organism, yet thin and flexible enough to fit within the cell. The combination of these properties greatly favors DNA collisions, which can knot and drive recombination of the DNA...

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Detalhes bibliográficos
Main Authors: Deibler, Richard W, Mann, Jennifer K, Sumners, De Witt L, Zechiedrich, Lynn
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904230/
https://ncbi.nlm.nih.gov/pubmed/17531098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-8-44
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