Differential in vitro inhibitory activity against HIV-1 of alpha-(1-3)- and alpha-(1-6)-D-mannose specific plant lectins : Implication for microbicide development

BACKGROUND: Plant lectins such as Galanthus nivalis agglutinin (GNA) and Hippeastrum hybrid agglutinin (HHA) are natural proteins able to link mannose residues, and therefore inhibit HIV-target cell interactions. Plant lectins are candidate for microbicide development. OBJECTIVE: To evaluate the act...

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Detalhes bibliográficos
Main Authors: Saïdi, Hela, Nasreddine, Nadine, Jenabian, Mohammad-Ali, Lecerf, Maxime, Schols, Dominique, Krief, Corinne, Balzarini, Jan, Bélec, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904181/
https://ncbi.nlm.nih.gov/pubmed/17565674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-5-28
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