Mannose-Specific Plant Lectins from the Amaryllidaceae Family Qualify as Efficient Microbicides for Prevention of Human Immunodeficiency Virus Infection

The plant lectins derived from Galanthus nivalis (Snowdrop) (GNA) and Hippeastrum hybrid (Amaryllis) (HHA) selectively inhibited a wide variety of human immunodeficiency virus type 1 (HIV-1) and HIV-2 strains and clinical (CXCR4- and CCR5-using) isolates in different cell types. They also efficientl...

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Autores principales: Balzarini, Jan, Hatse, Sigrid, Vermeire, Kurt, Princen, Katrien, Aquaro, Stefano, Perno, Carlo-Federico, De Clercq, Erik, Egberink, Herman, Vanden Mooter, Guy, Peumans, Willy, Van Damme, Els, Schols, Dominique
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC521907/
https://ncbi.nlm.nih.gov/pubmed/15388446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.3858-3870.2004
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