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Methylation enrichment pyrosequencing: combining the specificity of MSP with validation by pyrosequencing

It has been suggested that detection of aberrant DNA methylation in clinical specimens such as sputum or saliva may be a valuable tumour biomarker. Any clinically applicable detection technique must combine high sensitivity with high specificity. In this study we describe methylation enrichment pyro...

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Autori principali: Shaw, Richard J., Akufo-Tetteh, Emily K., Risk, Janet M., Field, John K., Liloglou, Triantafillos
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904102/
https://ncbi.nlm.nih.gov/pubmed/16807314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl424
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